Lemon Bottle
A branded lipolytic injection from South Korea containing riboflavin (vitamin B2), lecithin (phosphatidylcholine), and bromelain (pineapple enzyme). Marketed as a fat-dissolving solution for localized fat reduction through direct injection into subcutaneous fat deposits. A cosmetic treatment for targeted areas rather than a systemic weight loss solution.
Half-Life
Components metabolized within hours; visible effects develop over 2-4 weeks
Half-Life Calculator →Typical Dosage
Localized injection: 1-5 vials injected directly into subcutaneous fat per session, depending on treatment area. Sessions spaced 1-2 weeks apart, 3-5 sessions recommended per treatment area. Administered by trained practitioners only.
Administration
Direct injection into subcutaneous fat (mesotherapy)
Mechanism of Action
Lemon Bottle uses a combination of three active ingredients that work through complementary mechanisms to achieve localized fat cell disruption. The primary active component is lecithin (phosphatidylcholine), an amphiphilic phospholipid that, when injected directly into subcutaneous fat, acts as a detergent on adipocyte cell membranes. Phosphatidylcholine inserts into the lipid bilayer of fat cells, destabilizing membrane integrity and causing cell lysis — physically rupturing fat cells and releasing their stored triglyceride contents into the surrounding interstitial space.
Bromelain, a proteolytic enzyme complex derived from pineapple stems, serves as the second active component. Once fat cells are ruptured, bromelain helps break down the released cellular debris and protein structures, facilitating the body's inflammatory cleanup response. It also has anti-inflammatory properties that may help moderate the significant tissue swelling that occurs after injection lipolysis. The third component, riboflavin (vitamin B2), is a precursor to FAD (flavin adenine dinucleotide), a coenzyme essential for mitochondrial fatty acid beta-oxidation.
The overall process relies on the body's natural inflammatory and metabolic clearance systems — macrophages phagocytose cellular debris, released fatty acids are transported to the liver for processing, and the treated area gradually reduces in volume over 2-4 weeks. It is important to note that this is a localized cosmetic treatment, not a systemic weight loss solution, and the scientific evidence supporting its efficacy is primarily anecdotal rather than derived from controlled clinical trials.
Regulatory Status
Not FDA approved. Not classified as a drug in most jurisdictions. Considered a cosmetic treatment. No regulatory oversight in many markets.
Risks & Safety
Common: swelling, bruising, redness, pain and tenderness at injection site lasting several days. Serious: tissue necrosis if injected incorrectly or into non-fat tissue, uneven fat reduction, skin surface irregularities. Rare: infection, allergic reaction to components, chronic induration. Quality and formulation vary significantly between suppliers. Not FDA approved as a medical device or drug.
Research Papers
No research papers indexed yet. Papers are fetched from PubMed weekly.
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